Foreword 3

Executive summary 4

Section 1 The 3C Framework as an interconnected system 5

1.1 Identifying combinations revisited 7

Section 2 From combinations to convergence dynamics 9

2.1 Patterns of value creation 10

2.2 Signals from the field 12

Cognitive robotic systems in healthcare 12

Digital twin ecosystems in advanced manufacturing 17

Intelligent grid systems in energy 22

Autonomous labs in life sciences 27

Non-invasive brain-computer interfaces 32

Section 3 The value of orchestration 37

3.1 Monetization pathways 39

The race to compounding advantage 42

Contributors 43

Endnotes 46