Title page

Contents

Executive Summary 7

Purpose and Background 8

American Pandemic Preparedness: Transforming Our Capabilities 8

White House Steering Committee for Pandemic Innovation 8

Progress Towards Implementation of Transformational Capabilities 9

I. Transforming Our Medical Defenses 9

II. Ensuring Situational Awareness 13

III. Strengthening Public Health Systems 15

IV. Building Core Capabilities 17

V. Managing the Mission 21

Key Goals Towards Implementation of Transformational Capabilities 21

Utilizing Current Infectious Disease Health Challenges to 'Exercise' Pandemic Preparedness 21

Achieving a 'Portfolio View' of U.S. Government Pandemic Preparedness Investment to Ensure Readiness and Maximize Impact 22

I. Transforming Our Medical Defenses 23

II. Ensuring Situational Awareness 26

III. Strengthening Public Health Systems 26

IV. Building Core Capabilities 27

V. Managing the Mission 30

Conclusion 30

Relevant Publications 31

Figure 1. Core Capabilities of the American Pandemic Preparedness Plan That Will Enable Transformative, Life-Saving Innovation in Pandemic Preparedness 9